Understandable, and thanks for laying your thinking. I think you’re right in that we differ due to our priors. I’m probably more sceptical of mechanistic grounding of claims in medicine, in general. This is partly due to my experience that there’s a poor correlation between how well medical interventions work in reality, and how well they should work given a seemingly strong mechanistic case. It’s probably also due to a scepticism I have in general, which I haven’t really justified.
Thanks for communicating so clearly—it helped me understand where my impressions were coming from, and where we disagree!
And just to clarify, there’s a huge black box in my mind between “inflammation decreases” and “depressive symptoms decrease.” I have no idea what the mechanisms are there!
Understandable, and thanks for laying your thinking. I think you’re right in that we differ due to our priors. I’m probably more sceptical of mechanistic grounding of claims in medicine, in general. This is partly due to my experience that there’s a poor correlation between how well medical interventions work in reality, and how well they should work given a seemingly strong mechanistic case. It’s probably also due to a scepticism I have in general, which I haven’t really justified.
Thanks for communicating so clearly—it helped me understand where my impressions were coming from, and where we disagree!
You’re welcome, and likewise!
And just to clarify, there’s a huge black box in my mind between “inflammation decreases” and “depressive symptoms decrease.” I have no idea what the mechanisms are there!