Bernadette,
Thank you for your very informative response. I must admit that my knowledge of EBM is much more limited than yours and is primarily Wikipedia-based.
The lines which particularly led me to believe that EBM favoured formal approaches rather than doctorsâ intuitions were:
âAlthough all medicine based on science has some degree of empirical support, EBM goes further, classifying evidence by its epistemologic strength and requiring that only the strongest types (coming from meta-analyses, systematic reviews, and randomized controlled trials) can yield strong recommendations; weaker types (such as from case-control studies) can yield only weak recommendationsâ
âWhether applied to medical education, decisions about individuals, guidelines and policies applied to populations, or administration of health services in general, evidence-based medicine advocates that to the greatest extent possible, decisions and policies should be based on evidence, not just the beliefs of practitioners, experts, or administrators.â
Criticism of EBM: âResearch tends to focus on populations, but individual persons can vary substantially from population norms, meaning that extrapolation of lessons learned may founder. Thus EBM applies to groups of people, but this should not preclude clinicians from using their personal experience in deciding how to treat each patient.â
Perhaps the disagreement comes from my unintentional implication that the two camps were diametrically opposed to each other.
I agree that they are âboth fundamentally important when you act in the real worldâ and that evidence based giving /â evidence based medicine are not the last word on the matter and need to be supplemented by reason. At the same time though, I think there is an important distinction between maximising expected utility and being averse to ambiguity.
For example, to the best of my knowledge, the tradeoff between donating to SCI ($1.23 per treatment) and Deworm the World Initiative ($0.50 per treatment), is that DWI has demonstrated higher cost effectiveness but with a wider confidence interval (less of a track record). Interestingly, this actually sounds similar to your EGDT example. I therefore donate to SCI because I prefer to be confident in the effect. I think this distinction also applies to XRisk vs. development.
Thank you all for some great responses and apologies for my VERY late reply. This post was intended to âtest an idea/âprovoke a responseâ and thereâs some really good discussion here.