For the new R21 vaccine, WHO is currently conducting prequalification of the production facilities. As far as I understand, African governments have to wait for prequalification to finish for before they can apply for subsidized procurement and rollout through UNICEF and GAVI.
For both RTS,S and R21, there are some logistical difficulties due to the vaccines’ 4 dose schedule (First three 1 month apart—doesn’t fit all too well into existing vaccination schedules) cold-chain requirements, and timing peak immunity with the seasonality of malaria.
Lastly since there already exists cost-effective counter-measures, it’s unclear how to balance new vaccine efforts against existing measures.
There’s a few I know of:
For the new R21 vaccine, WHO is currently conducting prequalification of the production facilities. As far as I understand, African governments have to wait for prequalification to finish for before they can apply for subsidized procurement and rollout through UNICEF and GAVI.
For both RTS,S and R21, there are some logistical difficulties due to the vaccines’ 4 dose schedule (First three 1 month apart—doesn’t fit all too well into existing vaccination schedules) cold-chain requirements, and timing peak immunity with the seasonality of malaria.
Lastly since there already exists cost-effective counter-measures, it’s unclear how to balance new vaccine efforts against existing measures.