I was curious about your suggestion that a lot of researchers think that basically all biomedical research is gain/loss of function.
Not completely clear on what the context the researchers were speaking to but a standard strategy in figuring out what genes do is to knock out (loss of function) the gene of interest in a model organism and observe what happens. Synthetic biology also has a lot of ‘gain of function’ engineering e.g. make microbes produce insulin.
Not completely clear on what the context the researchers were speaking to but a standard strategy in figuring out what genes do is to knock out (loss of function) the gene of interest in a model organism and observe what happens. Synthetic biology also has a lot of ‘gain of function’ engineering e.g. make microbes produce insulin.