This is possibly interesting, but it would need more argument / detail. At the moment, mainly I’d view it as an interesting vector for gene editing a bunch of neurons. I’m skeptical of things like “add a bunch of BDNF” increasing intelligence much, but I could maybe be convinced otherwise.
Probably for me to want to suggest that someone fund a project on this, you’d need an expert on board, who can explain well what’s been tried, what the bottlenecks are, what you’re going to try that’s different, why it would plausibly work, why it would be able to support the cargo, what the cargo is supposed to do, etc.
Well, I have some details regarding microbial nootropic evolution on my page. I’ll leave that for now but happy to discuss if prodded.
With regards to your comment about what has been tried before, you have to keep in mind that people generally have not tried to improve IQ so directly. There has been a lack of projects and resources in these areas.
For example many of the transgenic mouse experiments that have improved intelligence have been small projects that were one-off, focused on a single gene or mutation. To my knowledge there has not been a large-scale or directed project to seriously pursue the prospect of developing intelligence enhancement.
Even domestication projects have been rather limited, IIRC often resulting in lower intelligence(?).
This is possibly interesting, but it would need more argument / detail. At the moment, mainly I’d view it as an interesting vector for gene editing a bunch of neurons. I’m skeptical of things like “add a bunch of BDNF” increasing intelligence much, but I could maybe be convinced otherwise.
Probably for me to want to suggest that someone fund a project on this, you’d need an expert on board, who can explain well what’s been tried, what the bottlenecks are, what you’re going to try that’s different, why it would plausibly work, why it would be able to support the cargo, what the cargo is supposed to do, etc.
Well, I have some details regarding microbial nootropic evolution on my page. I’ll leave that for now but happy to discuss if prodded.
With regards to your comment about what has been tried before, you have to keep in mind that people generally have not tried to improve IQ so directly. There has been a lack of projects and resources in these areas.
For example many of the transgenic mouse experiments that have improved intelligence have been small projects that were one-off, focused on a single gene or mutation. To my knowledge there has not been a large-scale or directed project to seriously pursue the prospect of developing intelligence enhancement.
Even domestication projects have been rather limited, IIRC often resulting in lower intelligence(?).
What I mean is, what’s been tried regarding using bacteria as persistent delivery mechanisms in the brain.