On 1 I think you are making a few common assumptions & the world may actually be more bottlenecked on broadly implementing existing ideas, thus we need higher average intelligence around the world for that implementation.
And a more general point, a lot of genes associated with higher intelligence are also associated with introversion/anti-socialness & with various mental abnormalities like OCD & others. By optimizing purely for IQ in genes you may be creating less collaborative & less happy individuals.
the world may actually be more bottlenecked on broadly implementing existing ideas, thus we need higher average intelligence around the world for that implementation.
I suppose we’re bottlenecked on both? I’m thinking of things like
curing cancer
curing all those other diseases
figuring out how to make aligned AGI
figuring out how to convince people to not make AGI
figuring out how to improve group epistemics, especially given social media and the internet
figuring out how society can work out its values better, given all the present constraints (poor incentives, etc.)
figuring out how to broadly implement existing ideas
etc.
And a more general point, a lot of genes associated with higher intelligence are also associated with introversion/anti-socialness & with various mental abnormalities like OCD & others. By optimizing purely for IQ in genes you may be creating less collaborative & less happy individuals.
I agree this would be a potentially significant concern if true, but I don’t think it’s mostly true, or at least I haven’t seen evidence for this and I’ve seen evidence against. Can you point to what you’re thinking of? The main thing I’m aware of in this vein is a slight (~.2, depending on source and the exact question) positive correlation between IQ and autism. IQ and other clinical mental conditions tend to be negatively correlated.
Note also that to a significant extent parents using reprogenetics can, if they want, avoid much undesired pleiotropy by also genomically vectoring against risk for autism etc.; and scientists can build polygenic scores for IQ or similar which exclude genes known to have pleiotropy with those other conditions. That’s not necessarily perfect, but I would guess it can feasibly be pretty effective.
Savage, Jeanne E., Philip R. Jansen, Sven Stringer, et al. “Genome-Wide Association Meta-Analysis in 269,867 Individuals Identifies New Genetic and Functional Links to Intelligence.” Nature Genetics 50, no. 7 (2018): 912–19. https://doi.org/10.1038/s41588-018-0152-6.
On 1 I think you are making a few common assumptions & the world may actually be more bottlenecked on broadly implementing existing ideas, thus we need higher average intelligence around the world for that implementation.
And a more general point, a lot of genes associated with higher intelligence are also associated with introversion/anti-socialness & with various mental abnormalities like OCD & others. By optimizing purely for IQ in genes you may be creating less collaborative & less happy individuals.
I suppose we’re bottlenecked on both? I’m thinking of things like
curing cancer
curing all those other diseases
figuring out how to make aligned AGI
figuring out how to convince people to not make AGI
figuring out how to improve group epistemics, especially given social media and the internet
figuring out how society can work out its values better, given all the present constraints (poor incentives, etc.)
figuring out how to broadly implement existing ideas
etc.
I agree this would be a potentially significant concern if true, but I don’t think it’s mostly true, or at least I haven’t seen evidence for this and I’ve seen evidence against. Can you point to what you’re thinking of? The main thing I’m aware of in this vein is a slight (~.2, depending on source and the exact question) positive correlation between IQ and autism. IQ and other clinical mental conditions tend to be negatively correlated.
For example, Savage et al. [1] state:
Their supplementary figure 10:
(from https://static-content.springer.com/esm/art%3A10.1038%2Fs41588-018-0152-6/MediaObjects/41588_2018_152_MOESM1_ESM.pdf)
Note also that to a significant extent parents using reprogenetics can, if they want, avoid much undesired pleiotropy by also genomically vectoring against risk for autism etc.; and scientists can build polygenic scores for IQ or similar which exclude genes known to have pleiotropy with those other conditions. That’s not necessarily perfect, but I would guess it can feasibly be pretty effective.
Savage, Jeanne E., Philip R. Jansen, Sven Stringer, et al. “Genome-Wide Association Meta-Analysis in 269,867 Individuals Identifies New Genetic and Functional Links to Intelligence.” Nature Genetics 50, no. 7 (2018): 912–19. https://doi.org/10.1038/s41588-018-0152-6.