I’m less optimistic about the use of surveys on whether people think tryptamines will/did work:
‘And do they work?’ doesn’t seem like a question that will be accurately answered by asking people whether it worked for them. (Reversion to the mean being my main concern.)
Non-users are asked whether tryptamines ‘could be effective for treating your cluster headaches’, which could be interpreted as a judgement on whether it works for anyone or whether it will work for them (for which the correct answer seems to be ‘maybe’). Users are asked whether it worked for them specifically. Directly computing the difference between these answers doesn’t seem meaningful.
I’m less optimistic about the use of surveys on whether people think tryptamines will/did work:
‘And do they work?’ doesn’t seem like a question that will be accurately answered by asking people whether it worked for them. (Reversion to the mean being my main concern.)
Non-users are asked whether tryptamines ‘could be effective for treating your cluster headaches’, which could be interpreted as a judgement on whether it works for anyone or whether it will work for them (for which the correct answer seems to be ‘maybe’). Users are asked whether it worked for them specifically. Directly computing the difference between these answers doesn’t seem meaningful.