If we were spending $10M a year instead of $1.5M on sequencing, how much less than 0.2% of people would have to be infected before an alert was raised?
How should I feel about 0.2%? Where is 0.2% on the value spectrum from no alert system and an alert system that triggered on a single infection?
That’s an important question that I don’t have the answer to, sorry!
How many people’s worth of wastewater can be tested with $1.5M of sequencing?
This isn’t a question of limits, but of diminishing returns to sampling from additional sewersheds. Which also depends a lot on how different the sewersheds are from each other.
It’s pretty close to linear: do 10x more sequencing and it goes from 0.2% to 0.02%. You can play with our simulator here: https://​​data.securebio.org/​​simulator/​​
That’s an important question that I don’t have the answer to, sorry!
This isn’t a question of limits, but of diminishing returns to sampling from additional sewersheds. Which also depends a lot on how different the sewersheds are from each other.