It would be awesome to see a follow up post from yourself or someone else on the following:
- what are the centers currently working on AAV - who is funding this work - what are the gaps in research - what are the gaps in funding
I would love to hear more thoughts on: Future research must focus on:
Engineering novel AAV capsids to avoid immune recognition.
Developing larger-capacity variants or split-genome strategies.
Scaling up manufacturing for equitable access.
If successful, AAV vaccines could reshape pandemic preparedness, offering single-dose, durable, customizable vaccines for both global health and low-resource settings.
Thanks, Swan. My collaborator at the University of Waterloo, is workinging on AAV vaccine platform design. Our model of collaboration is this, his lab is strong in design, he does all the engineering in Canada and sends to me here in Nigeria for testing. Funding has been a huge challenge. At the moment We are evaluating Phage vaccine platforms too. Not many people fund this as well
Thanks for writing this post! I am glad that the list of short-term projects is still useful!
This is a great overview!
It would be awesome to see a follow up post from yourself or someone else on the following:
- what are the centers currently working on AAV
- who is funding this work
- what are the gaps in research
- what are the gaps in funding
I would love to hear more thoughts on:
Future research must focus on:
Engineering novel AAV capsids to avoid immune recognition.
Developing larger-capacity variants or split-genome strategies.
Scaling up manufacturing for equitable access.
If successful, AAV vaccines could reshape pandemic preparedness, offering single-dose, durable, customizable vaccines for both global health and low-resource settings.
Thanks, Swan. My collaborator at the University of Waterloo, is workinging on AAV vaccine platform design. Our model of collaboration is this, his lab is strong in design, he does all the engineering in Canada and sends to me here in Nigeria for testing. Funding has been a huge challenge. At the moment We are evaluating Phage vaccine platforms too. Not many people fund this as well