Executive summary: Despite efficacy results falling short of expectations, the ex-Alvea employee highlights important scientific contributions and valuable lessons from the company’s bold effort to rapidly develop a DNA vaccine during the pandemic.
Key points:
The South Africa trial made scientific contributions like testing unusually high DNA vaccine doses and including a licensed comparator.
Key lessons include the value of experience, remote hiring, medical countermeasures, and drug development best practices.
The culture and team were exceptional in relentlessly pursuing ambitious goals.
Partnerships and parallelizing vendors were crucial to move quickly.
Quality management systems help avoid disasters.
Funders enabling talented teams to obsessively pursue good is inspirational.
This comment was auto-generated by the EA Forum Team. Feel free to point out issues with this summary by replying to the comment, andcontact us if you have feedback.
Executive summary: Despite efficacy results falling short of expectations, the ex-Alvea employee highlights important scientific contributions and valuable lessons from the company’s bold effort to rapidly develop a DNA vaccine during the pandemic.
Key points:
The South Africa trial made scientific contributions like testing unusually high DNA vaccine doses and including a licensed comparator.
Key lessons include the value of experience, remote hiring, medical countermeasures, and drug development best practices.
The culture and team were exceptional in relentlessly pursuing ambitious goals.
Partnerships and parallelizing vendors were crucial to move quickly.
Quality management systems help avoid disasters.
Funders enabling talented teams to obsessively pursue good is inspirational.
This comment was auto-generated by the EA Forum Team. Feel free to point out issues with this summary by replying to the comment, and contact us if you have feedback.