For those with a strong suffering focus, there are reasons to worry about an intelligent future even if you think suffering in fundamental physics dominates, because intelligent agents seem to me more likely to want to increase the size or vivacity of physics rather than decrease it, given generally pro-life, pro-sentience sentiments (or, if paperclip maximizers control the future, to increase the number of quasi-paperclips that exist).
For those with a strong suffering focus, there are reasons to worry about an intelligent future even if you think suffering in fundamental physics dominates, because intelligent agents seem to me more likely to want to increase the size or vivacity of physics rather than decrease it, given generally pro-life, pro-sentience sentiments (or, if paperclip maximizers control the future, to increase the number of quasi-paperclips that exist).