The gene also has some kind of selective disadvantage. (If we are lucky, the disadvantage will be something like “increased nutritional requirements” which is not a big problem in the present day.)
From looking at Wikipedia’s description of orexin it does brown fat activation which is essentially burning calories for nothing but warmth.
One of the drugs which is orexin agonist that is currently in clinical trials was earlier used as a weightloss drug.
It looks like “increased nutritional requirements” is part of the selective disadvantage.
From looking at Wikipedia’s description of orexin it does brown fat activation which is essentially burning calories for nothing but warmth.
One of the drugs which is orexin agonist that is currently in clinical trials was earlier used as a weightloss drug.
It looks like “increased nutritional requirements” is part of the selective disadvantage.