Executive summary: The cost-effectiveness of malaria vaccines like R21 is uncertain and potentially much worse than bednets or seasonal malaria chemoprevention. More research is warranted before advocating for rollout.
Key points:
Malaria vaccines may cost over $25 per person protected versus under $3 for bednets, with similar efficacy. This 10x difference merits investigation.
Key uncertainties include future costs as production scales, efficacy duration, and impact on severe malaria. Interaction effects with nets are also unclear.
An updated cost-effectiveness analysis is proposed, focusing on R21 versus nets, incorporating new data, but avoiding full red-teaming.
Even if less cost-effective, advocacy might be reasonable if it unlocks additional funding or enables elimination.
More evidence is needed before confidently advocating for rollout over alternative interventions.
This comment was auto-generated by the EA Forum Team. Feel free to point out issues with this summary by replying to the comment, andcontact us if you have feedback.
Executive summary: The cost-effectiveness of malaria vaccines like R21 is uncertain and potentially much worse than bednets or seasonal malaria chemoprevention. More research is warranted before advocating for rollout.
Key points:
Malaria vaccines may cost over $25 per person protected versus under $3 for bednets, with similar efficacy. This 10x difference merits investigation.
Key uncertainties include future costs as production scales, efficacy duration, and impact on severe malaria. Interaction effects with nets are also unclear.
An updated cost-effectiveness analysis is proposed, focusing on R21 versus nets, incorporating new data, but avoiding full red-teaming.
Even if less cost-effective, advocacy might be reasonable if it unlocks additional funding or enables elimination.
More evidence is needed before confidently advocating for rollout over alternative interventions.
This comment was auto-generated by the EA Forum Team. Feel free to point out issues with this summary by replying to the comment, and contact us if you have feedback.