Executive summary: The Nucleic Acid Observatory (NAO) team provides updates on their progress over the past 6 months in wastewater sequencing, pooled individual sequencing, nucleic acid tracers, sequencing data analysis, cost modeling, and organizational changes to detect stealth pandemics.
Key points:
Developed and optimized protocols for extracting nucleic acids from wastewater samples, including influent, sludge, and airplane waste.
Collaborating with experts to adapt custom metagenomic sequencing protocols and compare results from different groups.
Starting a new effort to collect and sequence pooled nasal swab samples from public places.
Published a white paper and detailed reviews comparing sampling strategies for early detection of stealth biothreats.
Redesigned and reimplemented the metagenomic sequencing pipeline for improved scalability and performance.
Conducted cost modeling and theoretical analysis to understand the cost and efficacy of detecting stealth pandemics via metagenomic sequencing.
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Executive summary: The Nucleic Acid Observatory (NAO) team provides updates on their progress over the past 6 months in wastewater sequencing, pooled individual sequencing, nucleic acid tracers, sequencing data analysis, cost modeling, and organizational changes to detect stealth pandemics.
Key points:
Developed and optimized protocols for extracting nucleic acids from wastewater samples, including influent, sludge, and airplane waste.
Collaborating with experts to adapt custom metagenomic sequencing protocols and compare results from different groups.
Starting a new effort to collect and sequence pooled nasal swab samples from public places.
Published a white paper and detailed reviews comparing sampling strategies for early detection of stealth biothreats.
Redesigned and reimplemented the metagenomic sequencing pipeline for improved scalability and performance.
Conducted cost modeling and theoretical analysis to understand the cost and efficacy of detecting stealth pandemics via metagenomic sequencing.
This comment was auto-generated by the EA Forum Team. Feel free to point out issues with this summary by replying to the comment, and contact us if you have feedback.