As a heuristic, if a problem is suffered by wealthy people, then it’s not a good marginal use of resources.
Global poverty is an EA cause area because it’s cost-effective, because people in extreme poverty can’t buy the things they need even when they’re really important.
Factory-farmed animals are even less able to help themselves than people in extreme poverty.
I haven’t considered the issue for more than 60 seconds, but my gut impression is that there won’t be cost-effective menopause interventions because wealthy and powerful women also experience menopause, so if there are good ways to make menopause less harmful, then those ways will already be being pursued.
There are highly effective treatments for menopause, particularly hormone replacement therapy (HRT). The production cost of estradiol itself is very low at the pharmaceutical level, but the price increases significantly by the time it reaches patients. Costs also vary by delivery method: oral tablets are typically the least expensive, but they carry a higher risk of side effects such as blood clots due to first-pass metabolism in the liver. Ttransdermal options like patches and gels are generally safer, though more costly to produce. In most cases, progesterone must also be added, which further increases the overall cost of treatment.
However, cost is only part of the issue. A major barrier is the lack of education and awareness among healthcare providers. Many clinicians receive limited training in menopause management, which can make accessing appropriate care difficult, even in high-income countries most physicians don’t learn about menopause treatments. Because of that women are often prescribed treatments like antidepressants for their symptoms instead of being offered HRT, which is often a more effective and appropriate option.
I agree that it might be a more complicated problem to solve unless you can make it manufactured hormones cheaper and solve the current global shortage, but I would suggest you spend more than 60 seconds thinking about it, especially since it’s going to affect people around you directly and it’s vastly mismanaged issue.
Rich people are visibly not investing enough in existential risk reduction, so my heuristic fails in this case.
Another related heuristic is that people are more likely to invest in immediate problems that already affect them, and less likely to invest in future problems, especially speculative future problems. Menopause is the former and existential risk is the latter.
As a heuristic, if a problem is suffered by wealthy people, then it’s not a good marginal use of resources.
Global poverty is an EA cause area because it’s cost-effective, because people in extreme poverty can’t buy the things they need even when they’re really important.
Factory-farmed animals are even less able to help themselves than people in extreme poverty.
I haven’t considered the issue for more than 60 seconds, but my gut impression is that there won’t be cost-effective menopause interventions because wealthy and powerful women also experience menopause, so if there are good ways to make menopause less harmful, then those ways will already be being pursued.
There are highly effective treatments for menopause, particularly hormone replacement therapy (HRT). The production cost of estradiol itself is very low at the pharmaceutical level, but the price increases significantly by the time it reaches patients. Costs also vary by delivery method: oral tablets are typically the least expensive, but they carry a higher risk of side effects such as blood clots due to first-pass metabolism in the liver. Ttransdermal options like patches and gels are generally safer, though more costly to produce. In most cases, progesterone must also be added, which further increases the overall cost of treatment.
However, cost is only part of the issue. A major barrier is the lack of education and awareness among healthcare providers. Many clinicians receive limited training in menopause management, which can make accessing appropriate care difficult, even in high-income countries most physicians don’t learn about menopause treatments. Because of that women are often prescribed treatments like antidepressants for their symptoms instead of being offered HRT, which is often a more effective and appropriate option.
I agree that it might be a more complicated problem to solve unless you can make it manufactured hormones cheaper and solve the current global shortage, but I would suggest you spend more than 60 seconds thinking about it, especially since it’s going to affect people around you directly and it’s vastly mismanaged issue.
I take it you don’t support existential risk reduction then? After all, rich people will be killed along with everyone else.
Rich people are visibly not investing enough in existential risk reduction, so my heuristic fails in this case.
Another related heuristic is that people are more likely to invest in immediate problems that already affect them, and less likely to invest in future problems, especially speculative future problems. Menopause is the former and existential risk is the latter.