Agreed that the linear vs non-linear issue is a major outstanding issue. My rough sense now is that you capture more of the benefits at higher levels of blood pressure (less so at lower levels/for healthier people) - so diminishing returns—but in general I don’t have a good answer and it’s something I’ll have to get a better sense of via expert interviews.
Agreed that the linear vs non-linear issue is a major outstanding issue. My rough sense now is that you capture more of the benefits at higher levels of blood pressure (less so at lower levels/for healthier people) - so diminishing returns—but in general I don’t have a good answer and it’s something I’ll have to get a better sense of via expert interviews.