As part of the larger effort of building an early detection center for novel pathogens, a smaller self-sustaining version is needed for remote locations. The ideal early-detection center would not only have surveillance stations in the largest hubs and airports of the world, but also in as many medium sized ones as possible. For this it is needed to provide a ready-made, small and transportable product which allows meta-genomic surveillance of wastewater or air ventilation. One solution would be designing a workflow utilizing the easily scalable and portable technology of nanopore sequencing and combining it with a workflow to extract nucleic acids from wastewater. The sharing of instructions on how to build and use this method could lead to a “do it yourself” (DIY) and decentralized version of a nucleic acid observatory. Instead of staffing a whole lab at a central location, it would be possible to only have one or two personnel in key locations who use this product to sequence samples directly and only transmit the data to the larger surveillance effort.
DIY decentralized nucleic acid observatory
Biorisk and Recovery from Catastrophes
As part of the larger effort of building an early detection center for novel pathogens, a smaller self-sustaining version is needed for remote locations. The ideal early-detection center would not only have surveillance stations in the largest hubs and airports of the world, but also in as many medium sized ones as possible. For this it is needed to provide a ready-made, small and transportable product which allows meta-genomic surveillance of wastewater or air ventilation. One solution would be designing a workflow utilizing the easily scalable and portable technology of nanopore sequencing and combining it with a workflow to extract nucleic acids from wastewater. The sharing of instructions on how to build and use this method could lead to a “do it yourself” (DIY) and decentralized version of a nucleic acid observatory. Instead of staffing a whole lab at a central location, it would be possible to only have one or two personnel in key locations who use this product to sequence samples directly and only transmit the data to the larger surveillance effort.