I’m glad to see SCD on the list. But I feel compelled to point out that SCD is 100% preventable with carrier genetic screening and IVF/PGT-M (pre-implantation genetic testing). Thus any strategy to address SCD should definitely include increasing access to IVF/PGT in low resource countries.
Thus any strategy to address SCD should definitely include increasing access to IVF/PGT in low resource countries.
That’s a pretty bold claim. Are you sure that would be more cost-effective than the newborn screening and treatment intervention proposed in that post? IVF seems pretty expensive compared to the costs of screening and treatment.
Not sure if a similar one has been done for SCD. But it’s not hard to imagine that eradication of a disease in a population is much more cost-effective (especially in the long, long term) than continuing to create billions more people with SCD and treating them with increasingly expensive therapies eg gene therapies (despite what pharmaceutical companies would have you believe).
I’m glad to see SCD on the list. But I feel compelled to point out that SCD is 100% preventable with carrier genetic screening and IVF/PGT-M (pre-implantation genetic testing). Thus any strategy to address SCD should definitely include increasing access to IVF/PGT in low resource countries.
That’s a pretty bold claim. Are you sure that would be more cost-effective than the newborn screening and treatment intervention proposed in that post? IVF seems pretty expensive compared to the costs of screening and treatment.
Here is an analysis of Huntington’s Disease.
https://pubmed.ncbi.nlm.nih.gov/35618525/
Not sure if a similar one has been done for SCD. But it’s not hard to imagine that eradication of a disease in a population is much more cost-effective (especially in the long, long term) than continuing to create billions more people with SCD and treating them with increasingly expensive therapies eg gene therapies (despite what pharmaceutical companies would have you believe).