Feels like in the real world you describe in which few/no cause areas are actually satiated for funding, neglectedness is of interest mainly in how it interacts with tractability.
If your small amount of effort kickstarts an area of research rather than merely adds some marginal quantity of additional research or funding, you might get some sort of multiplier on your efforts, assuming others find your case persuasive. And certain problems that have being neglected due to the relative obscurity/rarity of who/what they affect might be an indication that more tractable interventions exist (if there is a simple cure for common cancers it is remarkable we have not found it yet; conversely certain obscure diseases have been the subject of comparatively little research). On the other hand, the relationship doesn’t always run that way: some causes like world peace are neglected precisely because however important they might be, there doesn’t appear to be an efficacious solution.
Feels like in the real world you describe in which few/no cause areas are actually satiated for funding, neglectedness is of interest mainly in how it interacts with tractability.
If your small amount of effort kickstarts an area of research rather than merely adds some marginal quantity of additional research or funding, you might get some sort of multiplier on your efforts, assuming others find your case persuasive. And certain problems that have being neglected due to the relative obscurity/rarity of who/what they affect might be an indication that more tractable interventions exist (if there is a simple cure for common cancers it is remarkable we have not found it yet; conversely certain obscure diseases have been the subject of comparatively little research). On the other hand, the relationship doesn’t always run that way: some causes like world peace are neglected precisely because however important they might be, there doesn’t appear to be an efficacious solution.