Of all the global priorities, I gravitate toward those that focus on improving physical and mental health. As someone who deals with chronic pain and is in between jobs, nothing consumes my attention more than alleviating physical and mental suffering. I am curious if anyone in the community spends their work life thinking and working on increasing longevity, eliminating chronic pain, improving athletic performance, or improving individual reasoning or cognition.
Not sure how helpful this is to you, but the Happier Lives Institute does research on mental health and chronic pain. See e.g. this recent post on pain relief, and this one evaluating a mental health intervention (but also this response, and this response to the response).