I should clarify: RCTs are obviously generally >> even a very well controlled propensity score matched quasi-experiment, but I just don’t think the former is ‘bulletproof’ anymore. The former should update your priors more but if you look at the variability among studies in meta-analyses, even among low-risk-of-bias RCTs, I’m now much less easily swayed by any single one.
I should clarify: RCTs are obviously generally >> even a very well controlled propensity score matched quasi-experiment, but I just don’t think the former is ‘bulletproof’ anymore. The former should update your priors more but if you look at the variability among studies in meta-analyses, even among low-risk-of-bias RCTs, I’m now much less easily swayed by any single one.