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My impression is the latter and something like an irrational degree of trust in our medical institutions which generally don’t seem to entertain it, status quo bias.
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Classic serotonin model seems obsolete, but e.g. Jaminet posits a direct role for infection there via tryptophan theft in metabolic pathway, encouraged quinolinic acid production.
Those would be awesome… but it feels kind of gratuitous here. I was just trying to introduce this hypothesis crudely, rather than delve into “argue for a particular model with a line of evidence” territory. I consider this a possible interpretation or extrapolation, based on evidence available to me at time that was presented, of mental illness akin to an interpretation of QM or the Fermi hypothesis or AI.
Aside rant: If one were trying to argue for a model a list of various models would be very useful. To my horror I wasn’t able to find such a list of models already out there for a researcher to use by quickly Googling with my phone. May need to look in recent Google books listings more deeply. Compiling one on net would likely be a worthwhile exercise.
Intuition finds ideas but rigor sorts them out, this post was shooting for first category. I was shooting for spitballing, brainstorming/open discussion/thinking out loud in this post and curious to hear any assumptions or evidence that readers think are against it it. But this is a heated topic in an intellectual community with a high value on rigor which may discourage this sort of idea exploration and feedback, idk