Different medications get metabolized at different rates. If you were taking one that peaks after ~8 hours (like extended-release venlafaxine), evening timing might work better.
The first antidepressant I tried gave me nausea for much of the day when I took it in the morning. Taking it at night helped a lot because I slept through the part where I felt sick. This is how I learned “complain to your prescriber if you’re having side effects” because sometimes they have simple ideas that help.
Worth a try! Different meds are activating (make you more alert / awake) vs sedating, so it’s also worth noticing if an evening dose makes it harder to sleep.
Thank you! And thank you so much for your podcasts—like I mentioned in the post I found them really helpful and relatable and am grateful for you sharing so much!
I’m on buproprion xl and generally they don’t recommend taking it at night because it can cause insomnia but I’m really lucky and have never really had problems with that. Instead, I just found waking up in the morning extremely difficult—I often woke up sad and just wanted to stay in bed and keep sleeping (even if I had slept a really long time). Due to the extended release, taking it at night means that peak effects are now happening in the mornings when I was most sad / low motivation before. So that was honestly just really great for me.
So glad you’ve found ways to significantly improve your wellbeing!!
Can I ask why you think this helped so much?
Different medications get metabolized at different rates. If you were taking one that peaks after ~8 hours (like extended-release venlafaxine), evening timing might work better.
The first antidepressant I tried gave me nausea for much of the day when I took it in the morning. Taking it at night helped a lot because I slept through the part where I felt sick. This is how I learned “complain to your prescriber if you’re having side effects” because sometimes they have simple ideas that help.
Thanks! I have this nausea problem, so I’m going to try taking mine at night :) (checked and it seems fine/safe)
Worth a try! Different meds are activating (make you more alert / awake) vs sedating, so it’s also worth noticing if an evening dose makes it harder to sleep.
Thank you! And thank you so much for your podcasts—like I mentioned in the post I found them really helpful and relatable and am grateful for you sharing so much!
I’m on buproprion xl and generally they don’t recommend taking it at night because it can cause insomnia but I’m really lucky and have never really had problems with that. Instead, I just found waking up in the morning extremely difficult—I often woke up sad and just wanted to stay in bed and keep sleeping (even if I had slept a really long time). Due to the extended release, taking it at night means that peak effects are now happening in the mornings when I was most sad / low motivation before. So that was honestly just really great for me.