Whether avoiding *extreme suffering* such as cluster headaches, migraines, kidney stones, CRPS, etc. is an important, tractable, and neglected cause. I personally think that due to the long-tails of pleasure and pain, and how cheap the interventions would be, focusing our efforts on e.g. enabling cluster headaches sufferers to access DMT would prevent *astronomical amounts of suffering* at extremely low costs.
The key bottleneck here might be people’s ignorance of just *how bad* these kinds of suffering are. I recommend reading the “long-tails of pleasure and pain” article linked above to get a sense of why this is a reasonable interpretation of the situation.
Whether avoiding *extreme suffering* such as cluster headaches, migraines, kidney stones, CRPS, etc. is an important, tractable, and neglected cause. I personally think that due to the long-tails of pleasure and pain, and how cheap the interventions would be, focusing our efforts on e.g. enabling cluster headaches sufferers to access DMT would prevent *astronomical amounts of suffering* at extremely low costs.
The key bottleneck here might be people’s ignorance of just *how bad* these kinds of suffering are. I recommend reading the “long-tails of pleasure and pain” article linked above to get a sense of why this is a reasonable interpretation of the situation.