I don’t know what you mean? You can look at existing interventions that primarily help very young people (neonatal or childhood vitamin supplementation) v.s. a comparably-effective interventions that target adults or older people (e.g. cash grants, schistosomiasis)
There are multiple GiveWell charities in both categories, so this is just saying you should weight towards the ones that target older folks by maybe a factor of 2x or more, v.s. what givewell says (they assume the world won’t change much)
I think this is a good point about precise phrasing, but I think the argument still basically goes through that insects should be treated as extremely important in expectation. You can eliminate the two envelope problem by either make the numbers fixed/concrete, or you can use conditional probabilities.
Namely, “50% to be 10,000x as important as human suffering | insect suffering matters” = 50% chance there’s huge stakes in the world, far more than we thought.
“50% to be 0.0001x as important as human suffering | insect suffering doesn’t matter at all” = 50% chance the stakes are much smaller, in line with what we thought.
Which makes it clear the first world should be prioritized
More intuitively: suppose you thought there was an 50% chance you prevent a holocaust-level (10,000,000 lives) event happening to humans, but a 50% chance that this intervention would be completely useless. Alternately, you could do a normal intervention to save 1000 lives.
You could say “the normal intervention as a 50% chance to be ~infinitely more valuable than the holocaust-prevention thing”
But it’s obvious you should do the holocaust prevention thing. Because here it’s more obvious what the comparative/conditional stakes are. In one possible world, the ‘world you can affect’ is vastly larger, and that world should be prioritized.
Caveats: ignoring longtermist arguments, and the probability insects matter is << 50%