[Question] Is there an analysis that estimates possible timelines for arrival of easy-to-create pathogens?

Look­ing for a re­view of ex­pected fu­ture im­prove­ments in syn­thetic-biol­ogy tech­nolo­gies and the like, and a re­sult­ing ex­pected timeline for the ca­pa­bil­ity of in­di­vi­d­u­als se­cretly man­u­fac­tur­ing pathogens ca­pa­ble of mas­sive dam­age.